Three of Seven BRCA1 Mutations Definitively Linked to Cancer Development

05/14/2013 19:26:08

Spanish researchers have definitively linked three mutations in the BRCA1 (breast cancer 1, early onset) gene to the development of hereditary forms of breast and ovarian cancer while another four mutations were found not to be implicated in cancer occurrence.... ...

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A new cost-effective genome assembly process

05/14/2013 19:25:27

The U.S. Department of Energy Joint Genome Institute (DOE JGI) is among the world leaders in sequencing the genomes of microbes, focusing on their potential applications in the fields of bioenergy and environment.... ...

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Method makes it easier to separate useful stem cells from 'problem' ones for therapies

04/24/2013 23:10:58

Pluripotent stem cells can turn, or differentiate, into any cell type in the body, such as nerve, muscle or bone, but inevitably some of these stem cells fail to differentiate and end up mixed in with their newly differentiated daughter cells.... ...

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Molecular Pathways in the Hypothalamus Lead to Hypertension and Cardiovascular Disease

04/24/2013 23:10:38

A recent paper linked overexpression of mTORC1 (mammalian target of rapamycin complex 1) activity in the hypothalamus to the development of cardiovascular diseases.... ...

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Researchers Identify Inflammation's Key Negative Regulator

04/24/2013 23:10:08

Researchers working with a genetically engineered mouse model found that blocking the activity of the enzyme PDE4B (phosphodiesterase 4B) suppressed inflammation by increasing the expression of the deubiquitinase enzyme CYLD (cylindromatosis (turban tumor syndrome)).... ...

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Scientist identifies protein molecule used to maintain adult stem cells in fruit flies

04/24/2013 23:10:05

Understanding exactly how stem cells form into specific organs and tissues is the holy grail of regenerative medicine. Now a UC Santa Barbara researcher has added to that body of knowledge by determining how stem cells produce different types of "daughter" cells in Drosophila (fruit flies).... ...

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Fractalkine Treatment Alleviates Symptoms of Type II Diabetes

04/24/2013 23:10:03

Treatment of mouse diabetes models and in vitro cultures of human pancreatic cells with the protein fractalkine alleviated symptoms of type II diabetes by increasing insulin secretion and improving glucose tolerance.... ...

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"Love handles" melt away at the push of a button

04/24/2013 23:09:59

Researchers at the University of Bonn decode a kind of trigger switch for the conversion of fat cells... ...

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Scientists map all possible drug-like chemical compounds

04/24/2013 23:09:36

Drug developers may have a new tool to search for more effective medications and new materials.... ...

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Scientists find antibody that transforms bone marrow stem cells directly into brain cells

04/24/2013 23:09:18

In a serendipitous discovery, scientists at The Scripps Research Institute (TSRI) have found a way to turn bone marrow stem cells directly into brain cells.... ...

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